Desmin

Rb, 0.5 ml Conc.

Artikelnummer:1-DE075-05
Menge:
Technische Daten
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Kontrolle:Skeletal muscle
Zelluläre Lokalisation:Cytoplasmic
Fixierung:1) NOTOXhisto 2) Formalin
Anwendung AK:IHC(p),IHC(f)
Immunogen:Synthetic peptide of human Desmin C-terminal
Ig Unterklasse:IgG
Spezies:Rabbit
Klon:Polyclonal
Format AK:Concentrate
Reaktivität AK:Human, others not tested.
Synonyme:CMD1I, CSM1, CSM2, DES, FLJ12025, FLJ39719, FLJ41013, FLJ41793, Intermediate filament protein, OTTHUMP00000064865.
Verfügbar in folgenden Ländern:world wide (except US)
Status:IVD
Beschreibung

Desmin is a type III intermediate filament that is found on smooth, skeletal and cardiac muscle, primarily near the periphery of Z lines in sarcomeres. This antibody reacts with tumors of myoid origin including leiomyomas, rhabdomyomas and perivascular cells of glomus tumors of the skin. It is used to demonstrate the myogenic components/derivation of tumors and to distinguish mesothelioma from carcinoma.

Literatur

[1] Paulin D and Li Z (2004) Desmin: a major intermediate filament protein essential for the structural integrity and function of muscle. Exp Cell Res. 301(1):1-7.
[2] Parham DM, Webber B, Holt H et al. (1991) Immunohistochemical Study of Childhood Rhabdomyosarcomas and Related Neoplasms. Cancer. 67(12):3072-80.

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