Cytokeratin 19

Rb, 0.5 ml Conc.

Artikelnummer:1-CY200-05
Menge:
Technische Daten
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Kontrolle:Bladder, colon carcinoma, colon mucosa, thyroid carcinoma
Zelluläre Lokalisation:Cytoplasmic
Fixierung:1) NOTOXhisto 2) Formalin
Anwendung AK:IHC(p),IHC(f)
Immunogen:Synthetic peptide of human CK19 C-terminal
Ig Unterklasse:IgG
Spezies:Rabbit
Klon:Polyclonal
Format AK:Concentrate
Reaktivität AK:Human, others not tested.
Synonyme:CK-19, CK 19, 40 kDa keratin intermediate filament, CK 19, ck19, Cytokeratin 19, k19, k1cs, Keratin 19, Keratin type I 40 kD, Keratin type i 40kD, Keratin type I cytoskeletal 19, krt19, mgc15366.
Verfügbar in folgenden Ländern:world wide (except US)
Status:IVD
Beschreibung

Keratins are cytoplasmic intermediate filament proteins expressed by stratified and simple-type epithelial cells. Cytokeratin 19 is a type I keratin that is the smallest known keratin and in contrast to all other keratin does it have no designated partner for filament formation. This antibody detects a variety of epithelium and epithelial malignancies including adenocarcinomas of colon, stomach, pancreas, biliary tract, liver and breast.

Literatur

[1] Ma H, Xu S, Yan J et al. (2014): The value of tumor markers in the diagnosis of papillary thyroid carcinoma alone and in combination. Pol J Pathol. 65(3):202-9.
[2] Kawai T, Yasuchika K, Ishii T et al. (2015): Keratin 19, a Cancer Stem Cell Marker in Human Hepatocellular Carcinoma. Clin Cancer Res. 21(13):3081-91.
[3] Jain R, Fischer S, Serra S and Chetty R (2010: The use of Cytokeratin 19 (CK19) immunohistochemistry in lesions of the pancreas, gastrointestinal tract, and liver. Appl Immunohistochem Mol Morphol. 18(1):9-15.

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