Cytokeratin 14

LL002, Ms

Technische Daten
Status:In Vitro Diagnostic Use (IVD)
Ig Unterklasse:IgG3
Immunogen:Cytokeratin 14
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092) or ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Zelluläre Lokalisation:Cytoplasmic
Kontrolle:Squamous carcinoma, squamous mucosa
Change(s) made:Complete revision
Synonyme:Keratin type I cytoskeletal 14, CK-14, keratin-14, K14, KRT14, EBS3, EBS4, NFJ
Verfügbar in folgenden Ländern:worldwide

Keratins are cytoplasmic intermediate filament proteins expressed by epithelial cells. Cytokeratin 14 is a type I keratin that is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium and mesothelial cells in various tissues including prostate and breast. A cocktail of CK14, its corresponding partner CK5 and p63 is useful to detect the basal-like phenotype of breast carcinoma and to differentiate normal and prostate cancer.