Cyclin E1

Rb

Artikelnummer:CY022-H_RUO
Menge:
Technische Daten
Status:Research Use Only (RUO)
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of rat Cyclin E1
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Zelluläre Lokalisation:Nuclear, cytoplasmic is observed
Kontrolle:Placenta, breast cancer
Change(s) made:Complete revision
Synonyme:CCNE 1, CCNE, CCNE1, Cyclin E1, Cyclin Es, Cyclin Et, CyclinE, G1/S specific cyclin E.
Verfügbar in folgenden Ländern:worldwide
Beschreibung

Cyclin E1 belongs to the family of cyclins whose members regulate cell cycle progression by interacting with cyclin dependent kinases. It is essential for the control of the cell cycle at the G1/S (start) transition. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.

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