Caudal type homeo box 2/CDX2

Rb, 1 ml RTU

Technische Daten
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Kontrolle:Human gastric adenocarcinoma, colon, colon adenocarcinoma
Zelluläre Lokalisation:Nuclear
Fixierung:1) NOTOXhisto 2) Formalin
Anwendung AK:IHC(p),IHC(f)
Immunogen:Synthetic peptide of human CDX-2
Ig Unterklasse:IgG
Format AK:Ready-to-use
Reaktivität AK:Human, others not tested.
Synonyme:cau-dal-related homeobox transcription factor 2, Caudal type homeo box 2, Caudal type homeobox protein 2, caudal type homeobox transcription factor 2, CDX 2, CDX 3, CDX3, Homeobox protein CDX-2, Homeobox protein CDX2.
Verfügbar in folgenden Ländern:world wide (except US)

CDX2 is a caudal-related homeobox transcription factort that is expressed in the nuclei of intestinal epithelium and has a function in proliferation and differentiation of intestinal cells. This antibody detects primary and metastatic colorectal carcinomas, intestinal metaplasia of the stomach and intestinal type gastric cancer.


[1] Scholl C, Bansal D, Döhner K et al. (2007): The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis. J Clin Invest. 117(4): 1037-1048.
[2] Liu Q, Teh M, Ito K et al. (2007): CDX2 expression is progressively decreased in human gastric intestinal metaplasia, dysplasia and cancer. Mod Pathol. 20(12):1286-97.