Carcinoembryonic antigen/CD66e
Rb, 1 ml RTU
Technische Daten
Reaktivität AK: | Human, others not tested. | Format AK: | Ready-to-use | Klon: | Polyclonal | Spezies: | Rabbit | Ig Unterklasse: | IgG | Immunogen: | CEA | Anwendung AK: | IHC(p),IHC(f) | Fixierung: | 1) NOTOXhisto 2) Formalin | Zelluläre Lokalisation: | Cytoplasmic | Kontrolle: | Colon, lung, stomach, breast, associated adenocarcinomas | Lagerung AK: | Store at 2 - 8 °C. Do not use after expiration date indicated on the vial. | Synonyme: | Carcinoembryonic antigen, Carcinoembryonic antigen related cell adhesion molecule 5, CD66e, CEA, CEACAM5, DKFZp781M2392, Meconium antigen 100, OTTHUMP00000199032, OTTHUMP00000199033, OTTHUMP00000199034 | Verfügbar in folgenden Ländern: | world wide (except US) | Status: | IVD |
Beschreibung
Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion and is produced during fetal development. It is present in the epithelia of various tissues. This antibody is useful to assist in the distinction between adenocarcinoma and mesotheliomas, along with other markers such as calretinin, CK 5/6, D2-40, HBME-1, Napsin A, MOC-31, and Ber-EP4. It detects adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary and endocervix.
Literatur
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recognition in the Ig superfamily. Identification of precise
subdomains in carcinoembryonic antigen required for
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CEACAM5 monoclonal antibody, CC4, suppresses
colorectal tumor growth and enhances NK cells-mediated
tumor immunity. PLoS One. 6(6):e21146.
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(2011) Phylogenetic discordance of human and canine
carcinoembryonic antigen (CEA, CEACAM) families, but
striking identity of the CEA receptors will impact
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panel of markers in the differential diagnosis of
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detection of recurrent disease following curative resection
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4.
[7] Duffy MJ (2001) Carcinoembryonic antigen as a
marker for colorectal cancer: is it clinically useful? Clin
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[8] Gold P and Freedman SO (1965) Specific
carcinoembryonic antigens of the human digestive
system. J Exp Med. 122(3):467-81. [9] Röcken C, et al.: Arch Pathol Lab Med. 2000;124(11):1704-6.
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