Calponin 1/CNN1
Rb, 0.5 ml Conc.
Technische Daten
Reaktivität AK: | Human, others not tested. | Format AK: | Concentrate | Klon: | Polyclonal | Spezies: | Rabbit | Ig Unterklasse: | IgG | Immunogen: | Synthetic peptide of human Calponin 1 | Anwendung AK: | IHC(p),IHC(f) | Fixierung: | 1) NOTOXhisto 2) Formalin | Zelluläre Lokalisation: | Cytoplasmic | Kontrolle: | Appendix, breast, uterus, leiomyoma | Lagerung AK: | Store at 2 - 8 °C. Do not use after expiration date indicated on the vial. | Synonyme: | Basic calponin, Calponin 1, Calponin-1, Calponin 1 basic smooth muscle, Calponin H1 smooth muscle, Calponin1, Calponins basic, CNN 1, CNN1, Sm Calp, SMCC, CNN1_HUMAN. | Verfügbar in folgenden Ländern: | world wide (except US) | Status: | IVD |
Beschreibung
Calponin is a calcium-binding protein, which interacts with actin, tropomyosin and calmodulin in context of smooth muscle contraction mechanism. This antibody detects invasion of breast lesions, malignant fibrous histiocytoma of bone and adenoid cystic carcinoma of salivary gland.
Literatur
[1] Liu R and Jin (2016) Calponin isoforms CNN1, CNN2
and CNN3: Regulators for actin cytoskeleton functions in
smooth muscle and non-muscle cells. Gene. 585(1):143-
153.
[2] Strasser P, Gimona M, Moessler H et al (1993)
Mammalian calponin. Identification and expression of
genetic variants. FEBS Lett. 330(1):13-8.
[3] Ueda T, Araki N, Mano M et al (2002) Frequent
expression of smooth muscle markers in malignant
fibrous histiocytoma of bone. J Clin Pathol. 55(11):853-8.
[4] Liu Y, Wu X, Wang G et al. (2019) CALD1, CNN1, and
TAGLN identified as potential prognostic molecular
markers of bladder cancer by bioinformatics analysis.
Medicine (Baltimore) 98(2):e13847.
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