Calponin 1/CNN1

Rb, 1 ml RTU

Artikelnummer:2-CA103-07
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human Calponin 1
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Zelluläre Lokalisation:Cytoplasmic
Kontrolle:Appendix, breast, uterus, leiomyoma
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Synonyme:Basic calponin, Calponin 1, Calponin-1, Calponin 1 basic smooth muscle, Calponin H1 smooth muscle, Calponin1, Calponins basic, CNN 1, CNN1, Sm Calp, SMCC, CNN1_HUMAN.
Verfügbar in folgenden Ländern:world wide (except US)
Status:IVD
Beschreibung

Calponin is a calcium-binding protein, which interacts with actin, tropomyosin and calmodulin in context of smooth muscle contraction mechanism. This antibody detects invasion of breast lesions, malignant fibrous histiocytoma of bone and adenoid cystic carcinoma of salivary gland.

Literatur

[1] Liu R and Jin (2016) Calponin isoforms CNN1, CNN2 and CNN3: Regulators for actin cytoskeleton functions in smooth muscle and non-muscle cells. Gene. 585(1):143- 153.
[2] Strasser P, Gimona M, Moessler H et al (1993) Mammalian calponin. Identification and expression of genetic variants. FEBS Lett. 330(1):13-8.
[3] Ueda T, Araki N, Mano M et al (2002) Frequent expression of smooth muscle markers in malignant fibrous histiocytoma of bone. J Clin Pathol. 55(11):853-8.
[4] Liu Y, Wu X, Wang G et al. (2019) CALD1, CNN1, and TAGLN identified as potential prognostic molecular markers of bladder cancer by bioinformatics analysis. Medicine (Baltimore) 98(2):e13847.

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