Technische Daten
Status:Research Use Only (RUO)
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human CTAG1B
Vorbehandlung:ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Zelluläre Lokalisation:Cytoplasmic
Kontrolle:Testis, myxoid and round cell liposarcoma
Change(s) made:Complete revision
Synonyme:Autoimmunogenic cancer/testis antigen NY ESO 1, Autoimmunogenic cancer/testis antigen NY-ESO-1, Cancer antigen 3, Cancer/testis antigen 1, Cancer/testis antigen 1B, Cancer/testis antigen 6.1, CT6.1, CTAG 1, CTAG 1B, CTAG, CTAG1, CTAG1A, CTAG1B, CTG1B_HUMAN, ESO 1, ESO1, L antigen family member 2, LAGE 2, LAGE 2 protein, LAGE 2B, LAGE-2, LAGE2, LAGE2 protein, LAGE2A, LAGE2B, New York esophageal squamous cell carcinoma 1, NY ESO 1, NYESO 1, NYESO1.
Verfügbar in folgenden Ländern:worldwide

Cancer/testis (CT) antigens are a category of tumor antigens with normal expression restricted to male germ cells in the testis but not in adult somatic tissues. In some cases, CT antigens are also expressed in ovary and in trophoblast. In malignancy, this gene regulation is disrupted, resulting in CT antigen expression in a proportion of tumors of various types. CT 1A/1B is expressed in testis and ovary and in a wide variety of cancers. It is detected in uterine myometrium, and from 18 weeks until birth in human fetal testis. In the adult testis, is strongly expressed in spermatogonia and in primary spermatocytes, but not in post-meiotic cells or in testicular somatic cells.