CEA31, Ms

Technische Daten
Status:In Vitro Diagnostic Use (IVD)
Ig Unterklasse:IgG1
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092) or ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Zelluläre Lokalisation:Cytoplasmic
Kontrolle:Adenocarcinoma of colon, normal colon
Change(s) made:Complete revision
EK Distributor €:-
EK Liste €:137
Synonyme:Carcinoembryonic antigen, Carcinoembryonic antigen related cell adhesion molecule 5, CD66e, CEA, CEACAM5, DKFZp781M2392, Meconium antigen 100, OTTHUMP00000199032, OTTHUMP00000199033, OTTHUMP00000199034
Verfügbar in folgenden Ländern:worldwide

Carcinoembryonic Antigen, also known as CD66e, is a cell surface protein and regulates differentiation and anoikis, tissue architecture, intercellular adhesion and other processes. CEA is a widely used tumor marker and has been found expressed in carcinomas from the gastrointestinal tract especially colorectal cancer and many types of epithelial tumors. The antibody is used as a tool to differentiate lung adenocarcinoma (positive) from mesothelioma (negative) and is also helpful in monitoring tumor progression.


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[2] Zheng C, Feng J, Lu D et al. (2011) A novel anti-CEACAM5 monoclonal antibody, CC4, suppresses colorectal tumor growth and enhances NK cells-mediated tumor immunity. PLoS One. 6(6):e21146.
[3] Weichselbaumer M, Willmann M, Reifinger M et al. (2011) Phylogenetic discordance of human and canine carcinoembryonic antigen (CEA, CEACAM) families, but striking identity of the CEA receptors will impact comparative oncology studies. PLoS Curr. 3:RRN1223.
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