CD41 (Cluster of Differentiation 41) belongs to the integrin family and interacts with CD61 to form the major platelet transmembrane glycoprotein complex (receptor CD41/CD61) which mediates platelet aggregation and adhesion. Upon blood vessel damage, this receptor binds to von Willebrand factor, fibrinogen, fibronectin and vitronectin. It is expressed on megakaryocyte-platelet lineage, and during early stages of hematopoietic differentiation.