CD4

Rb, 1 ml RTU

Artikelnummer:2-CD024-07
Menge:
Technische Daten
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Kontrolle:Tonsil
Zelluläre Lokalisation:Membranous
Fixierung:1) NOTOXhisto 2) Formalin
Anwendung AK:IHC(p),IHC(f)
Immunogen:Synthetic peptide of human CD4
Ig Unterklasse:IgG
Spezies:Rabbit
Klon:Polyclonal
Format AK:Ready-to-use
Reaktivität AK:Human, others not tested.
Synonyme:CD4 (L3T4), CD4 antigen (p55), CD4 Antigen , CD4 molecule, CD4 Receptor, CD4+ Lymphocyte deficiency, included, CD4mut, L3T4, Leu3, Ly-4, Lymphocyte antigen CD4, MGC165891, p55, T Cell Antigen T4 , T cell antigen T4/LEU3, T cell differentiation antigen L3T4, T cell OKT4 deficiency, included, T cell surface antigen T4/Leu 3 , T cell surface antigen T4/Leu3, T Cell Surface Glycoprotein CD4, W3/25, W3/25 antigen.
Verfügbar in folgenden Ländern:world wide (except US)
Status:IVD
Beschreibung

CD4 (Cluster of Differentiation 4) is a glycoprotein found on the surface of immune cells like T helper cells, monocytes, macrophages, and dendritic cells but not expressed on B-cells and immature thymocytes. This antibody reacts with CD4, identifying normal cells of T helper/inducer lineage in peripheral blood as well as most mature T-cell lymphomas (except aggressive NK-cell leukemia and extranodal NK/T-cell lymphoma). It helps to classify lymphocytes in inflammatory lesions and malignant lymphomas.

Literatur

[1] Isobe M, Huebner K, Maddon PJ et al. (1986): The gene encoding the T-cell surface protein T4 is located on human chromosome 12. Proc Natl Acad Sci U S A. 83(12):4399-402.
[2] Williamson SL, Steward M, Milton I (1998): New monoclonal antibodies to the T cell antigens CD4 and CD8. Production and characterization in formalin-fixed paraffin-embedded tissue. Am J Pathol. 152(6):1421-6.

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