CD25
  • CD25

CD25

Rb, 1 ml RTU

Artikelnummer:2-CD112-07
Menge:
Technische Daten
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Kontrolle:Lesions of mastocytosis, small bowel
Zelluläre Lokalisation:Cytoplasmic, membranous
Fixierung:1) NOTOXhisto 2) Formalin
Anwendung AK:IHC(p),IHC(f)
Immunogen:Synthetic peptide of human CD25
Ig Unterklasse:IgG
Spezies:Rabbit
Klon:Polyclonal
Format AK:Ready-to-use
Reaktivität AK:Human, others not tested.
Synonyme:Interleukin 2 receptor alpha chain, CD 25, CD25, CD25 antigen, IDDM10, IL 2 RA, IL 2 receptor alpha subunit, IL2 RA, IL2R, IL2RA, IL2RAC, Interleukin 2 Receptor Alpha, Interleukin 2 receptor alpha chain, Interleukin 2 receptor, Ly43, p55, T Cell Growth Factor Receptor, TAC Antigen, TCGFR.
Verfügbar in folgenden Ländern:world wide (except US)
Status:IVD
Beschreibung

CD25 (Cluster of Differentiation 25) is a low-affinity receptor for interleukin-2 (IL-2). It is found on activated B-cells, T-cells, some thymocytes, myeloid precursors and oligodendrocytes. This antibody has been used to distinguish between neoplastic mast cell aggregates and reactive proliferations in Systemic Mastocytosis. It detects B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas and tumor infiltrating lymphocytes.

Literatur

[1] Dong HY, Weisberger J, Liu Z and Tugulea S (2009): Immunophenotypic analysis of CD103+ Blymphoproliferative disorders: hairy cell leukemia and its mimics. Am J Clin Pathol. 131(4):586-95.
[2] Pardanani A (2015): Systemic mastocytosis in adults: 2015 update on diagnosis, risk stratification, and management. Am J Hematol. 90(3):250-62.
[3] Choy MY, Walker-Smith JA, Williams CB and MacDonald TT (1990): Differential expression of CD25 (interleukin-2 receptor) on lamina propria T cells and macrophages in the intestinal lesions in Crohn's disease and ulcerative colitis. Gut. 31(12):1365-70.

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