CD24

SN3, Ms

Artikelnummer:CD107-H_RUO
Menge:
Technische Daten
Kontrolle:Tonsil
Zelluläre Lokalisation:Membranous
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092) or ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Immunogen:Isolated human pre-B leukemia cell line
Ig Unterklasse:IgG
Spezies:Mouse
Status:Research Use Only (RUO)
Change(s) made:Complete revision
Synonyme:CD 24 , CD24 , CD24 antigen (small cell lung carcinoma cluster 4 antigen) , CD24 antigen , CD24 molecule , CD24_HUMAN , CD24A , GPI linked surface mucin , Heat stable antigen , HSA , Nectadrin , Signal transducer CD24 , Small cell lung carcinoma cluster 4 antigen.
Verfügbar in folgenden Ländern:worldwide
Beschreibung

CD24 is a sialoglycoprotein functioning as cell adhesion molecule. It is expressed at the surface of most B lymphocytes and differentiating neuroblasts, on neutrophils and neutrophil precursors from the myelocyte stage onwards. The protein is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface and contributes to a wide range of downstream signaling networks. It is crucial for neural development.[5] Cross-linking of CD24 on the surface of neutrophils induces apoptosis, and this appears to be defective in sepsis.

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