Technische Daten
| Lagerung AK: | Store at 2 - 8 °C. Do not use after expiration date indicated on the vial. | | Kontrolle: | Skin, thymus | | Zelluläre Lokalisation: | Membranous | | Fixierung: | 1) NOTOXhisto 2) Formalin | | Anwendung AK: | IHC(p),IHC(f) | | Immunogen: | Synthetic peptide of human CD1a | | Ig Unterklasse: | IgG | | Spezies: | Rabbit | | Klon: | Polyclonal | | Format AK: | Concentrate | | Reaktivität AK: | Human, others not tested. | | Synonyme: | CD1, CD1A Antigen, CD1a molecule, Cortical thymocyte antigen CD1A, Epidermal dendritic cell marker CD1a, FCB 6, FCB6, HTA 1, HTA1, hTa1 thymocyte antigen, R4, T Cell Surface Antigen Leu 6, T Cell Surface Antigen T6, T cell surface antigen T6/Leu 6, T Cell Surface Glycoprotein CD1A, T6, Thymocyte Antigen CD1A.
CD1D, CD1B, CD1b antigen, CD1b molecule, CD1C, CD1C antigen, CD1c molecule, CD1d molecule, Cd1d1, Cortical thymocyte antigen CD1C, Cortical thymocyte antigen CD1D, hTa1 thymocyte antigenLy38, Ly38, T cell surface glycoprotein CD1a, T cell surface glycoprotein CD1b, T cell surface glycoprotein CD1c, T cell surface glycoprotein CD1d, T6/Leu6. | | Verfügbar in folgenden Ländern: | world wide (except US) | | Status: | IVD |
Beschreibung
CD1a (Cluster of Differentiation 1a) belongs to the family of major histocompability complex (MHC) and presents antigens after binding to T-cell receptors on natural killer cells. This antibody detects cortical thymocytes, Langerhans' cells and dendritic cells as well as Langerhans' cell histiocytosis and T-lymphoblastic lymphoma/leukemia.
Literatur
[1] Hillenbrand EE, Neville AM and Coventry BJ (1999):
Immunohistochemical localization of CD1a-positive
putative dendritic cells in human breast tumours. Br J
Cancer. 79(5-6):940-4.
[2] West JA, Olsen SL, Mitchell JM et al. (2014):
Polyclonal T-cells express CD1a in Langerhans cell
histiocytosis (LCH) lesions. PLoS One. 24;9(10):e109586.
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