Technische Daten
Kontrolle:Monocyte cells, whole blood
Zelluläre Lokalisation:Cytoplasmic, membranous
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Immunogen:Synthetic peptide of human CD13
Ig Unterklasse:IgG
Status:Research Use Only (RUO)
Change(s) made:Complete revision
Synonyme:Aminopeptidase N, Alanyl aminopeptidase, Alanyl membrane aminopeptidase, Aminopeptidase M, Aminopeptidase N, ANPEP, APN, CD 13, CD13 antigen, gp150, hAPN, Lap 1, Lap1, Microsomal, aminopeptidase, Myeloid plasma membrane glycoprotein CD13, p150.
Verfügbar in folgenden Ländern:worldwide

CD13 (Cluster of Differentiation 13) is a broad specificity aminopeptidase that plays a role in final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. This antibody detects a 150 kDa protein, it is used as a marker for acute myeloid leukemia. CD13 is expressed in epithelial cells of the kidney, intestine, and respiratory tract; granulocytes, monocytes, fibroblasts, endothelial cells, cerebral pericytes at the blood-brain barrier, synaptic membranes of cells in the CNS, endometrial stromal cells, vasculature of tissues that undergo angiogenesis, in malignant gliomas and lymph node metastases from multiple tumor types, and in plasma. It is found to be elevated in plasma and effusions of cancer patients.