Technische Daten
Kontrolle:Human spleen
Zelluläre Lokalisation:Membranous
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Immunogen:Synthetic peptide of human CD11b
Ig Unterklasse:IgG
Status:Research Use Only (RUO)
Change(s) made:Complete revision
Synonyme:Antigen CD11b p170, CD11 antigen like family member B, CD11b antigen, CD49d, Cell surface glycoprotein MAC 1 alpha subunit, Cell Surface Glycoprotein MAC1 Alpha Subunit, Complement Component Receptor 3 Alpha, CR 3 alpha chain, CR3 Alpha Chain, CR3A, Integrin Alpha M, integrin alpha M complement component 3 receptor 3 subunit, Leukocyte Adhesion Receptor MO1, MAC 1, MAC1A, MGC117044, MO1A, Neutrophil Adherence Receptor, Cd11b, CD11b/CD18, F730045J24Rik, Ly-40, ITGAM, CR3A.
Verfügbar in folgenden Ländern:worldwide

CD11b is expressed on the surface of many leukocytes involved in the innate immune system, including monocytes, granulocytes, macrophages, and natural killer cells. It mediates inflammation by regulating leukocyte adhesion and migration and has been implicated in several immune processes. CD11b is also a receptor for fibrinogen, factor X and ICAM1. Expression is found on spleen cells, bone marrow cells and thymocytes and is commonly used as a microglial marker in nervous tissue.