Aurora A

Rb, 0.1 ml Conc.

Technische Daten
Reaktivität AK:Human, Mouse, Rat, please ask for further reactivities.
Format AK:Concentrate
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human Auroa A (31-110aa)
Anwendung AK:IHC(p*) *reported as working on paraffin,IHC(f),WB,ELISA
Fixierung:1) NOTOXhisto 2) Formalin
Lagerung AK:Aliquot and store at - 20 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Cytoplasmic
Synonyme:AIK, ARK1, AURA, AURKA, Aurora 2, Aurora A, Aurora Family Kinase 1, aurora kinase A, Aurora Related Kinase 1, Aurora/IPL1 Like Kinase, Aurora/IPL1 Related Kinase 1, AURORA2, AYK1, BRAK, Breast Tumor Amplified Kinase, BTAK, hARK1, IAK, IPL1 Aurora Related Kinase 1, IPL1 Related Kinase, MGC34538.
Verfügbar in folgenden Ländern:world wide

The Aurora kinases are a family of mitotic serine/threonine kinases that are essential for cell proliferation. They associate with microtubules during chromosome movement and segregation. Defects in this segregation can cause genetic instability, which is highly associated with tumorigenesis. Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, and during tumor development and progression. It is expressed in testis, skeletal muscle, thymus, and spleen. Overexpression is found in many human cancers including colon, ovarian, prostate, neuroblastoma, breast, and cervical cancer cell lines.