Catenin beta/CTNNB
Rb, 0.5 ml Conc.
Technische Daten
Reaktivität AK: | Human, others not tested. | Format AK: | Concentrate | Klon: | Polyclonal | Spezies: | Rabbit | Ig Unterklasse: | IgG | Immunogen: | Synthetic peptide of human Beta catenin | Anwendung AK: | IHC(p),IHC(f) | Fixierung: | 1) NOTOXhisto 2) Formalin | Zelluläre Lokalisation: | Nuclear, cytoplasmic, membranous | Kontrolle: | Breast, fibromatosis | Lagerung AK: | Store at 2 - 8 °C. Do not use after expiration date indicated on the vial. | Verfügbar in folgenden Ländern: | world wide (except US) | Status: | IVD |
Beschreibung
Catenin beta plays an important role in the Wnt signaling pathway and is essential for cell contacts. It has a major impact on development, cell proliferation and differentiation. A mutation in the gene leads to nuclear accumulation, which has been demonstrated in fibromatosis of the breast and abdomen.
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