SATB2

QR023, Rb

Artikelnummer:S002-H
Menge:
Technische Daten
Change(s) made:Complete revision
Status:In Vitro Diagnostic Use (IVD)
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human SATB2
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092) or ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Zelluläre Lokalisation:Nuclear
Kontrolle:Colon, colorectal cancer
Synonyme:SATB2, GLSS, SATB homeobox 2
Verfügbar in folgenden Ländern:worldwide
Beschreibung

SATB2 is a nuclear matrix protein that influences craniofacial formation mechanisms, such as jaw and palate development, and is part of a transcriptional network regulating skeletal development and osteoblast differentiation. It is highly expressed in adult and fetal brain, and weak expressed in liver, kidney, and spinal cord as well as some brain regions. Defects in the gene encoding SATB2 are the cause of cleft palate manifested in conjunction with severe mental retardation.

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