PMS2

QR009, Rb

Artikelnummer:P005-H
Menge:
Technische Daten
Change(s) made:Complete revision
Status:In Vitro Diagnostic Use (IVD)
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:PMS2
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092) or ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Zelluläre Lokalisation:Nuclear
Kontrolle:Colon
Synonyme:DNA mismatch repair gene homologue, H_DJ0042M02.9, HNPCC4, PMS 2, PMS1 protein homolog 2, PMS2 postmeiotic segregation increased 2, PMS2CL, PMSL2.
Verfügbar in folgenden Ländern:worldwide
Beschreibung

Mismatch repair endonuclease PMS2 is an enzyme that is involved in DNA mismatch repair. This gene is deficient in many patients with microsatellite instability and it is commonly associated with Hereditary Non-Polyposis Colon Cancer (HNPCC). This antibody is useful in screening patients and families for this condition and is utilized in an IHC panel that includes the antibodies MLH1, MSH2 and MSH6.

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