MLH1

QM003, Ms

Artikelnummer:M001-H
Menge:
Technische Daten
Change(s) made:Complete revision
Status:In Vitro Diagnostic Use (IVD)
Spezies:Mouse
Ig Unterklasse:IgG1
Immunogen:MLH1
Vorbehandlung:ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Zelluläre Lokalisation:Nuclear
Kontrolle:Colon carcinoma, colon mucosa
Synonyme:MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), COCA2, FCC2, HNPCC, HNPCC2, hMLH1
Verfügbar in folgenden Ländern:worldwide
Beschreibung

MLH1 is a gene that is involved in DNA mismatch repair. This gene is deficient in many patients with microsatellite instability and it is commonly associated with Hereditary Non-Polyposis Colon Cancer (HNPCC). This antibody is useful in screening patients and families for this condition and is utilized in an IHC panel that includes the antibodies MSH2, MSH6 and PMS2.

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