Alpha fetoprotein/AFP

Rb, 0.5 ml Conc.

Artikelnummer:1-AL047-05
Menge:
Technische Daten
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Kontrolle:Fetal liver
Zelluläre Lokalisation:Cytoplasmic
Fixierung:1) NOTOXhisto 2) Formalin
Anwendung AK:IHC(p),IHC(f)
Immunogen:Synthetic peptide of human AFP
Ig Unterklasse:IgG
Spezies:Rabbit
Klon:Polyclonal
Format AK:Concentrate
Reaktivität AK:Human, others not tested.
Synonyme:Alpha Fetoprotein, AFP, alpha 1 fetoprotein, alpha fetoglobulin, alpha Fetoprotein, Alpha fetoprotein precursor, FETA, HPAFP.
Verfügbar in folgenden Ländern:world wide (except US)
Status:IVD
Beschreibung

Alpha fetoprotein is a major plasma protein produced in liver and yolk sac during fetal development. It is the fetal form of serum albumin. This antibody recognizes endogenous levels of total AFP, especially in hepatocytes of fetal liver and hepatoma. Elevated levels of AFP in adults indicate lesions of liver, yolk sac carcinoma or other tumors. It reacts with germ-cell tumors and gonadal tumors.

Literatur

[1] Bergstrand CG and Czar B (1956) Demonstration of a new protein fraction in serum from the human fetus. Scand J Clin Lab Invest. 8(2):174.
[2] Anzai H, Kazama S, Kiyomatsu T et al. (2015) Alphafetoprotein- producing early rectal carcinoma: a rare case report and review. World J Surg Oncol. 13:180.
[3] Yamamoto R, Ishikura H, Azuma M et al. (1996) Alpha-fetoprotein production by a hepatoid adenocarcinoma of the uterus. J Clin Pathol. 49(5):420-2.

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