Adhesion related kinase/AXL

Rb, 7 ml RTU

Artikelnummer:2-AD043-13
Menge:
Technische Daten
Reaktivität AK:Human, Mouse, Rabbit, Rat, please ask for further reactivities.
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human AXL
Anwendung AK:IHC(p*) *reported as working on paraffin,IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Membraneous
Synonyme:Adhesion related kinase, Ark, AXL oncogene, AXL receptor tyrosine kinase, AXL transforming gene, AXL transforming sequence/gene, Oncogene AXL, Tyro7, Tyrosine protein kinase receptor UFO, UFO antibody.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

AXL is a member of the receptor tyrosine kinase subfamily. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors such as vitamin K dependent protein growth arrest specific gene 6, it is involved in the stimulation of cell proliferation, may function as a signal transducer between specific cell types of mesodermal origin, and mediates cell aggregation by homophilic binding. AXL is an oncogene associated with colon cancer, melanoma, chronic myelogenous leukemia.

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