Activating transcription factor 4/ATF4

Rb, 3 ml RTU

Artikelnummer:2-AC046-10
Menge:
Technische Daten
Reaktivität AK:Human, Mouse, Rat, Guinea pig
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human ATF4
Anwendung AK:IHC(p*) *reported as working on paraffin,IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Breast carcinoma
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Nuclear
Synonyme:Cyclic AMP response element binding protein 2, DNA binding protein TAXREB67, Activating Transcription Factor 4, ATF 4, ATF4 protein, CREB 2, CREB2, CREB-2, Cyclic AMP dependent transcription factor ATF 4, Tax Responsive Enhancer Element B67, TAXREB67, TXREB.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

Activating Transcription Factor 4 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulate transcription by binding cAMP response element in various genes which are important in cell growth and differentiation, in stress and immune responses. ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein. It also binds to the Tax-responsive element of the human T-cell lymphotropic virus type-I. It is localized in the cytoplasm, at the cell membrane and in the nucleus; it colocalizes with GABBR1 in hippocampal neuron dendritic membranes.

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