Actin, smooth muscle
1A4, Ms, 1 ml RTU
Technische Daten
| Reaktivität AK: | Human, others not tested. | | Format AK: | Ready-to-use | | Klon: | 1A4 | | Spezies: | Mouse | | Ig Unterklasse: | IgG/k | | Immunogen: | Actin of smooth muscle | | Anwendung AK: | IHC(p),IHC(f) | | Fixierung: | 1) NOTOXhisto 2) Formalin | | Zelluläre Lokalisation: | Cytoplasmic | | Kontrolle: | Smooth muscle | | Lagerung AK: | Store at 2 - 8 °C. Do not use after expiration date indicated on the vial. | | Synonyme: | alpha smooth muscle Actin, Actin alpha, ASMA, _ Actin, A-SMA, _ SMA, _-SMA, ASM-A, alpha-SMA, alpha SMA, AAT6, ACTA2, Actin alpha 2 smooth muscle aorta, Actin aortic smooth muscle, ACTSA, ACTVS, Alpha 2 actin, Alpha cardiac actin, Alpha-actin 2, Cell growth inhibiting gene 46 protein, Growth inhibiting gene 46,
ACTA_HUMAN,
Actin alpha 2 smooth muscle aorta,
Actin aortic smooth muscle,
Actin, aortic smooth muscle,
Alpha 2 actin,
Alpha actin 2,
Alpha cardiac actin,
Alpha-actin 2,
Alpha-actin-2,
Cell growth inhibiting gene 46 protein,
Cell growth-inhibiting gene 46 protein,
Growth inhibiting gene 46,
MYMY5 | | Verfügbar in folgenden Ländern: | world wide (except US) | | Status: | IVD |
Beschreibung
Actin is a major component of the cytoskeleton. This antibody reacts with actin of myofibroblasts and myoepithelial cells, no cross-reaction with actin of cardiac or skeletal muscle. Paired with Actin Muscle Specific, a discrimination between leiomyosarcoma and rhybdomyosarcoma is possible.
Literatur
[1] Gabbiani G, Ryan GB, Lamelin JP et al. (1973)
Human smooth muscle autoantibody. Its identification as
antiactin antibody and a study of its binding to
"nonmuscular" cells. Am J Pathol. 72(3):473-88.
[2] Gown AM, Vogel AM, Gordon D et al. (1985) A
smooth muscle-specific monoclonal antibody recognizes
smooth muscle actin isozymes. J Cell Biol. 100(3):807-
13.
[3] Vandekerckhove J and Weber K (1981) Actin typing
on total cellular extracts: a highly sensitive proteinchemical
procedure able to distinguish different actins.
Eur J Biochem. 113(3):595-603.
[4] Yuan SM (2015) _-Smooth Muscle Actin and ACTA2
Gene Expressions in Vasculopathies. Braz J Cardiovasc
Surg. 30(6):644-9.
[5] Johnson GD, Holborow EJ and Glynn LE (1965)
Antibody to smooth muscle in patients with liver disease.
Lancet 2:878-879.
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