ATM
Rb
Artikelnummer: | AT002-H_RUO |
Technische Daten
Change(s) made: | Complete revision | Kontrolle: | Breast | Zelluläre Lokalisation: | Nuclear | Vorbehandlung: | ProTaqs® Antigen Enhancer IV (Cat. No. 401602392) | Immunogen: | Synthetic peptide of human ATM | Ig Unterklasse: | IgG | Spezies: | Rabbit | Status: | Research Use Only (RUO) | EK Distributor €: | - | EK Liste €: | 699 | Synonyme: | ataxia telangiectasia mutated, AT complementation group A, AT complementation group C, AT complementation group D, AT complementation group E, AT mutated, AT protein, AT1, ATA, Ataxia telangiectasia gene mutated in human beings, ATC, ATDC, ATE, ATM, DKFZp781A0353, Human phosphatidylinositol 3 kinase homolog, MGC74674, Serine protein kinase ATM, T cell prolymphocytic leukemia, TEL1, TPLL. | Verfügbar in folgenden Ländern: | worldwide |
Beschreibung
ATM is a 370 kDa nuclear phosphoprotein involved in Ataxia Telangiectasia. It is a serine/threonine protein kinase which activates checkpoint signaling, apoptosis and genotoxic stresses, thereby acting as a DNA damage sensor. It is found in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, spleen, thymus, testis, ovary, small intestine, colon, and leukocytes.
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