ATM

Rb

Artikelnummer:AT002-H_RUO
Menge:
Technische Daten
Change(s) made:Complete revision
Kontrolle:Breast
Zelluläre Lokalisation:Nuclear
Vorbehandlung:ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Immunogen:Synthetic peptide of human ATM
Ig Unterklasse:IgG
Spezies:Rabbit
Status:Research Use Only (RUO)
Synonyme:ataxia telangiectasia mutated, AT complementation group A, AT complementation group C, AT complementation group D, AT complementation group E, AT mutated, AT protein, AT1, ATA, Ataxia telangiectasia gene mutated in human beings, ATC, ATDC, ATE, ATM, DKFZp781A0353, Human phosphatidylinositol 3 kinase homolog, MGC74674, Serine protein kinase ATM, T cell prolymphocytic leukemia, TEL1, TPLL.
Verfügbar in folgenden Ländern:worldwide
Beschreibung

ATM is a 370 kDa nuclear phosphoprotein involved in Ataxia Telangiectasia. It is a serine/threonine protein kinase which activates checkpoint signaling, apoptosis and genotoxic stresses, thereby acting as a DNA damage sensor. It is found in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, spleen, thymus, testis, ovary, small intestine, colon, and leukocytes.

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