Rb, 0.5 ml Conc.

Technische Daten
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Kontrolle:Human hepatocellular carcinoma
Zelluläre Lokalisation:Cytoplasmic
Fixierung:1) NOTOXhisto 2) Formalin
Anwendung AK:IHC(p),IHC(f)
Immunogen:Synthetic peptide of human Arg-1
Ig Unterklasse:IgG
Format AK:Concentrate
Reaktivität AK:Human, others not tested.
Synonyme:ARG 1, ARG1, ARGI1_HUMAN, Arginase1, Arginase liver, Arginase type I, Arginase I, ArginaseI, Arginase-1, Arginase1, Liver type arginase, Liver-type arginase, Type I arginase.
Verfügbar in folgenden Ländern:world wide (except US)

Arginase 1 catalyzes the conversion of arginine to ornithine and urea. It is expressed almost exclusively in the liver.


[1] Haraguchi Y, Takiguchi M, Amaya Y et al. (1987) Molecular cloning and nucleotide sequence of cDNA for human liver arginase. Proc Natl Acad Sci U S A 84(2):412-5.
[2] de Boniface J, Mao Y, Schmidt-Mende J et al. (2012) Expression patterns of the immunomodulatory enzyme arginase 1 in blood, lymph nodes and tumor tissue of early-stage breast cancer patients. Oncoimmunology 1(8):1305-1312.
[3] Fujiwara M1, Kwok S, Yano H et al. (2012) Arginase-1 is a more sensitive marker of hepatic differentiation than HepPar-1 and glypican-3 in fine-needle aspiration biopsies. Cancer Cytopathol. 120(4):230-7.
[4] Radwan NA and Ahmed NS (2012) The diagnostic value of arginase-1 immunostaining in differentiating hepatocellular carcinoma from metastatic carcinoma and cholangiocarcinoma as compared to HepPar-1. Diagn Pathol. 7:149.