Technische Daten
| Lagerung AK: | Store at 2 - 8 °C. Do not use after expiration date indicated on the vial. | | Kontrolle: | Human hepatocellular carcinoma | | Zelluläre Lokalisation: | Cytoplasmic | | Fixierung: | 1) NOTOXhisto 2) Formalin | | Anwendung AK: | IHC(p),IHC(f) | | Immunogen: | Synthetic peptide of human Arg-1 | | Ig Unterklasse: | IgG | | Spezies: | Rabbit | | Klon: | Polyclonal | | Format AK: | Concentrate | | Reaktivität AK: | Human, others not tested. | | Synonyme: | ARG 1, ARG1, ARGI1_HUMAN, Arginase1, Arginase liver, Arginase type I, Arginase I, ArginaseI, Arginase-1, Arginase1, Liver type arginase, Liver-type arginase, Type I arginase. | | Verfügbar in folgenden Ländern: | world wide (except US) | | Status: | IVD |
Beschreibung
Arginase 1 catalyzes the conversion of arginine to ornithine and urea. It is expressed almost exclusively in the liver.
Literatur
[1] Haraguchi Y, Takiguchi M, Amaya Y et al. (1987)
Molecular cloning and nucleotide sequence of cDNA for
human liver arginase. Proc Natl Acad Sci U S A
84(2):412-5.
[2] de Boniface J, Mao Y, Schmidt-Mende J et al. (2012)
Expression patterns of the immunomodulatory enzyme
arginase 1 in blood, lymph nodes and tumor tissue of
early-stage breast cancer patients. Oncoimmunology
1(8):1305-1312.
[3] Fujiwara M1, Kwok S, Yano H et al. (2012) Arginase-1
is a more sensitive marker of hepatic differentiation than
HepPar-1 and glypican-3 in fine-needle aspiration
biopsies. Cancer Cytopathol. 120(4):230-7.
[4] Radwan NA and Ahmed NS (2012) The diagnostic
value of arginase-1 immunostaining in differentiating
hepatocellular carcinoma from metastatic carcinoma and
cholangiocarcinoma as compared to HepPar-1. Diagn
Pathol. 7:149.
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