C3, Ms

Technische Daten
Kontrolle:Early fetal liver
Zelluläre Lokalisation:Cytoplasmic
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Ig Unterklasse:IgG2a/k
Status:In Vitro Diagnostic Use (IVD)
Change(s) made:Complete revision
Synonyme:AFP, Alpha fetoglobulin, Alpha fetoprotein precursor, Hereditary persistence of alpha fetoprotein (HPAFP)
Verfügbar in folgenden Ländern:worldwide

Alpha fetoprotein is a major plasma protein produced in liver and yolk sac during fetal development. It is the fetal form of serum albumin. This antibody recognizes endogenous levels of total AFP, especially in hepatocytes of fetal liver and hepatoma. Elevated levels of AFP in adults indicate lesions of liver, yolk sac carcinoma or other tumors. It reacts with germ-cell tumors and gonadal tumors.


[1] Bergstrand CG and Czar B (1956) Demonstration of a new protein fraction in serum from the human fetus. Scand J Clin Lab Invest. 8(2):174.
[2] Anzai H, Kazama S, Kiyomatsu T et al. (2015) Alphafetoprotein-producing early rectal carcinoma: a rare case report and review. World J Surg Oncol. 13:180.
[3] Yamamoto R, Ishikura H, Azuma M et al. (1996) Alpha-fetoprotein production by a hepatoid adenocarcinoma of the uterus. J Clin Pathol. 49(5):420-2.