Insulin like growth factor 2 mRNA binding protein 3/IMP3

Rb, 0.5 ml Conc.

Artikelnummer:1-IN090-05
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Concentrate
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human IMP3
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Zelluläre Lokalisation:Cytoplasmic, nuclear
Kontrolle:Human fetal liver tissue, esophageal carcinoma
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Synonyme:Insulin like growth factor 2 mRNA binding protein 3
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

IMP3, also known as Insulin like growth factor 2 mRNA binding protein 3, is an oncofetal protein that stabilizes IGF-II mRNA for trafficking and plays an important role in cell growth and migration. Expression is normally found in developing tissues during early embryogenesis in a variety of fetal tissues including the liver, lung kidney, thymus, and placenta. Only low or no level is found in normal adult tissues. IMP3 has been found in various malignant tumors of the lung, gastrointestinal tract, liver, endometrium, and bladder. It may play a role in tumor proliferation, invasion and metastasis.

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