Forkhead box protein A1/FOXA1

Rb, 1 ml RTU

Artikelnummer:2-FO020-07
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human FOXA1
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Zelluläre Lokalisation:Nuclear
Kontrolle:Breast carcinoma
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Synonyme:forkhead box A1, Forkhead box protein A1, FOX A1, FOXA1, FOXA1_HUMAN, hepatocyte nuclear factor 3 alpha, Hepatocyte nuclear factor 3-alpha, HNF 3A, HNF-3-alpha, HNF-3A, HNF3A, MGC33105, TCF 3A, TCF-3A, TCF3A, Transcription factor 3A
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

FOX proteins are transcription factors that play important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation, and life expectancy. Defining for FOX proteins is the forkhead box motif, a sequence of 80 to 100 amino acids, that binds to DNA. FOXA1 is a hepatocyte nuclear factor activating liver-specific transcripts such as albumin and transthyretin, and interacting with chromatin. It is highly expressed in prostate and ESR1-positive breast tumors. Overexpression is found in esophageal and lung adenocarcinomas.

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