CD23

Rb, 6 ml RTU

Artikelnummer:2-CD103-12
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human CD23
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Zelluläre Lokalisation:Membranous
Kontrolle:Tonsil, lymph node
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Verfügbar in folgenden Ländern:world wide (except US)
Status:IVD
Beschreibung

CD23 is an IgE receptor, that regulates IgE levels. It is a key molecule in B-cell activation and growth. CD23 is found on mature B-cells, activated macrophages, eosinophils, follicular dendritic cells and platelets. This antibody detects B-cell chronic lymphocytic leukemia, follicular dendritic cell tumors, mediastinal large B-cell lymphoma, the majority of centroblastic-centricytic lymphomas, a small fraction of centroblastic lymphomas, and rarely tumor cells in centrocytic lymphomas. It is non-reactive with mantle cell lymphoma.

Literatur

[1] Acharya M, Borland G, Edkins AL et al. (2010): CD23/Fc_RII: molecular multi-tasking. Clin Exp Immunol. 162(1):12-23.

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