CD1a

MTB1, Ms, 0.5 ml Conc.

Artikelnummer:1-CD002-05
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Concentrate
Klon:MTB1
Spezies:Mouse
Ig Unterklasse:IgG1/k
Immunogen:CD1a
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Zelluläre Lokalisation:Membranous
Kontrolle:Skin, thymus
Lagerung AK:Aliquot and store at - 20 °C. Do not use after expiration date indicated on the vial.
Synonyme:MTB1
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

CD1a (Cluster of Differentiation 1a) belongs to the family of major histocompability complex (MHC) and presents antigens after binding to T-cell receptors on natural killer cells. This antibody detects cortical thymocytes, Langerhans' cells and dendritic cells as well as Langerhans' cell histiocytosis and T-lymphoblastic lymphoma/leukemia.

Literatur

[1] Hillenbrand EE, Neville AM and Coventry BJ (1999): Immunohistochemical localization of CD1a-positive putative dendritic cells in human breast tumours. Br J Cancer. 79(5-6):940-4.
[2] West JA, Olsen SL, Mitchell JM et al. (2014): Polyclonal T-cells express CD1a in Langerhans cell histiocytosis (LCH) lesions. PLoS One. 24;9(10):e109586.

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