S100P

Rb, 6 ml RTU

Artikelnummer:2-S1026-12
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human S100P
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Zelluläre Lokalisation:Cytoplasmic, nuclear
Kontrolle:Placenta, urinary carcinoma, pancreatic ductal carcinoma
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

S100P is a member of the S100 family of proteins that contains 2 EF-hand calcium-binding motifs and that is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. It is expressed in the cytoplasm and/or nuclei of a variety of cells. S100P was initially identified in the placenta at rather high levels, in pancreatic ductal adenocarcinoma in pancreatic resection, and in fine needle aspiration biopsy specimens, and in the invasive component of cells of intraductal papillary mucinous neoplasms, including perineural, lymphatic, and minimal invasion. This antibody can be helpful in distinguishing adenocarcinoma from reactive epithelial changes on challenging bile duct biopsies, as well as urothelial carcinomas from other genitourinary neoplasms that enter into the differential diagnosis.

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