CD31/PECAM1

JC70, Ms, 1 ml RTU

Artikelnummer:2-CD126-07
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:JC70
Spezies:Mouse
Ig Unterklasse:IgG1/k
Immunogen:CD31
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Zelluläre Lokalisation:Cytoplasmic, membranous
Kontrolle:Appendix, placenta, tonsil
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Verfügbar in folgenden Ländern:world wide (except US)
Status:IVD
Beschreibung

CD31 (Cluster of Differentiation 31) is an integral membrane glycoprotein, that is found on the surface of endothelial cells, platelets and some hematopoetic cells. It plays a key role in removing aged neutrophils from the body. This antibody detects cells of arteries, arterioles, venules, veins, non-sinusoidal capillaries of different tissues as well as tumors of endothelial origin and vascular invasion of tumors.

Literatur

[1] Parums DV, Cordell JL, Micklem K et al. (1990): JC70: a new monoclonal antibody that detects vascular endothelium associated antigen on routinely processed tissue sections. J Clin Pathol. 43(9):752-7.
[2] Kuzu I, Bicknell R, Harris AL et al. (1992): Heterogeneity of vascular endothelial cells with relevance to diagnosis of vascular tumours. J Clin Pathol. 45(2):143-8.
[3] De Young BR, Frierson HF Jr, Ly MN et al. (1998): CD31 immunoreactivity in carcinomas and mesotheliomas. Am J Clin Pathol.110(3):374-7.

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