Cytokeratin 20

Rb, 6 ml RTU

Artikelnummer:2-CY203-12
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human CK20 C-terminal
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Zelluläre Lokalisation:Cytoplasmic
Kontrolle:Bladder, colon carcinoma, colon mucosa
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Verfügbar in folgenden Ländern:world wide (except US)
Status:IVD
Beschreibung

Keratins are cytoplasmic intermediate filament proteins expressed by epithelial cells. Cytokeratin 20 is a type I keratin that is a part of mature enterocytes and goblet cells and is specifically found in the gastric and intestinal mucosa. This antibody is useful in the differentiation of specific types of simple epithelial cells of the urinary tract as well as normal and malignantly transformed epithelia. It detects adenocarcinomas of the colon, stomach, pancreas and biliary system, mucinous ovarian tumors, transitional-cell and Merkel cell carcinomas.

Literatur

[1] Kummar S, Fogarasi M, Canova A et al. (2002): Cytokeratin 7 and 20 staining for the diagnosis of lung and colorectal adenocarcinoma. Br J Cancer. 86(12):1884-7.
[2] Chu P, Wu E and Weiss LM (2000): Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. Mod Pathol. 13(9):962-72.

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