CD30

Ber-H2, Ms, 6 ml RTU

Artikelnummer:2-CD123-12
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:Ber-H2
Spezies:Mouse
Ig Unterklasse:IgG1/k
Immunogen:CD30
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Zelluläre Lokalisation:Membranous
Kontrolle:Anaplastic large cell lymphoma, Hodgkin's lymphoma
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

CD30 is a cell membrane protein, that regulates activation of NF-kappaB and apoptosis. This antibody detects HodgkinÔs lymphoma, anaplastic large cell lymphomas, primary cutaneous CD30+ T-cell lymphoproliferative disorders and embryonal carcinomas.

Literatur

[1] Scholl C, Bansal D, Döhner K et al. (2007): The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis. J Clin Invest. 117(4): 1037-1048.
[2] Liu Q, Teh M, Ito K et al. (2007): CDX2 expression is progressively decreased in human gastric intestinal metaplasia, dysplasia and cancer. Mod Pathol. 20(12):1286-97.

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