CD3

PS1, Ms, 6 ml RTU

Artikelnummer:2-CD020-12
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:PS1
Spezies:Mouse
Ig Unterklasse:IgG2a
Immunogen:Recombinant non-glycosylated epsilon chain of CD3 protein
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Zelluläre Lokalisation:Membranous
Kontrolle:Tonsil
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

CD3 (Cluster of Differentiation 3) is a protein complex that is composed of five chains (gamma, delta, epsilon, zeta, eta) which associate with the T-cell antigen receptor (TCR). CD3 is involved in the development and survival of T-cells. This antibody detects T-cells and T-cell derived malignancies. It is known as the best allround T-cell marker. Clone PS1 detects the epsilon-subunit of TCR.

Literatur

[1] Mason DY, Cordell J, Brown M et al. (1989): Detection of T cells in paraffin wax embedded tissue using antibodies against a peptide sequence from the CD3 antigen. J Clin Pathol. 42(11):1194-200.
[2] Sommers CL, Dejarnette JB, Huang KJ et al. (2000): Function of CD3 epsilon-mediated signals in T cell development. Exp Med. 192(6):913-19.

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