14-3-3 epsilon

Rb, 1 ml Conc.

Artikelnummer:1-00001-07
Menge:
Technische Daten
Reaktivität AK:Human, Mouse, Rabbit, Rat, please ask for further reactivities.
Format AK:Concentrate
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human 14-3-3E C-terminal
Anwendung AK:IHC(p*) *reported as working on paraffin,IHC(f),WB,ELISA
Fixierung:1) NOTOXhisto 2) Formalin
Lagerung AK:Aliquot and store at - 20 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Cytoplasmic
Synonyme:14-3-3 epsilon, 14 3 3 E, 14 3 3 epsilon, 14 3 3E, 14-3-3 E, 14-3-3 protein epsilon, 14-3-3E, 1433E_HUMAN, KCIP 1, KCIP-1, KCIP1, MDCR, MDS, mitochondrial import stimulation factor L subunit, protein kinase C inhibitor protein-1, Protein kinase C inhibitor protein1, Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, epsilon polypeptide, tyrosine 3/tryptophan 5 -monooxygenase activation protein epsilon polypeptide, Tyrosine 3/tryptophan 5 monooxygenase activation protein epsilon polypeptide, YWHAE.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

This antibody is a member of the 14-3-3 family that have the ability to bind a multitude of functionally diverse signaling proteins, including kinases, phosphatases, and transmembrane receptors. 14-3-3 proteins are a family of conserved regulatory molecules expressed in all eukaryotic cells. 14-3-3 epsilon is an adapter protein that interacts with a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif, including CDC25 phosphatases, RAF1, and IRS1 proteins. Binding generally results in the modulation of the activity of the binding partner. It has been implicated in the pathogenesis of small cell lung cancer. It is localized in cytoplasm and melanosome.

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